ADVANTAGES OF KLOTHO PROTEIN

KIDNEY DISEASE

Klotho injections in animals slow the progression of kidney disfunction in chronic kidney disease (CKD) and for acute kidney injury (AKI) reduce the severity while promoting healing.

DECREASED KLOTHO & CHRONIC KIDNEY DISEASE

The level of Klotho in the blood has been shown to decline as the stage of kidney disease increases. Humans on dialysis show dramatically lower levels of Klotho than healthy individuals.

CKD chronic kidney disease

Source: Barker et al., Nephrology Dialysis Transplantation, 2015.

renal fibrosis

Source: Hu et al., Kidney International, 2017.

ejection

INJECTIONS SLOWS CKD & ADVERSE CARDIAC EFFECTS

In mice with chronic kidney disease, multiple injections of Klotho resulted in significantly less kidney and heart damage.

SIGNIFICANTLY REDUCED KIDNEY DAMAGE

Studies have shown that a single Klotho injection in animals shortly after AKI significantly reduced kidney damage vs. controls, as measured by levels of creatinine (lower is better). The result: reduced kidney damage and more complete recovery.

post injury

Source: Hu et al., Kidney International, 2010.

CONTACT: info@klotho.com COPYRIGHT @ 2017, KLOTHO THERAPEUTICS, INC. SAN DIEGO, CA. ALL RIGHTS RESERVED