Cancer
Klotho shows great promise in the treatment of many types of cancer in animal studies. Klotho suppresses tumor growth, inhibits metastases, reduces resistance to chemo-therapy drugs and improves survival. Cancer is the leading cause of death in the US and new cancer cases are expected to grow 70% over the next 20 years. Most cancers are not curable.
Source: Ligumsky et al., Molecular Cancer Research, 2015.
SUPPRESSES BREAST CANCER GROWTH
In animals, repeated injection of Klotho significantly slowed all measures of breast cancer growth: tumor size, weight and visual appearance. Importantly, Klotho was well tolerated.
IMPROVED SURVIVAL
Klotho injections significantly improved survival in animals transplanted with cancer cells.
Source: Doi et al., Journal of Biological Chemistry, 2011.
REDUCED METASTASES
Klotho injections significantly reduced the mean number of metastatic cancer lesions from 3 to 1 in animals that were transplanted with cancer cells.
Source: Doi et al., Journal of Biological Chemistry, 2011.