Changing the Face of Longevity Forever™

A biotechnology company which has developed a patented Human Klotho Protein with great potential to redefine society’s experience with aging.

Solving

LIVE WELL LONGER™

Aging is a complex biological process regulated by multiple intrinsic and extrinsic factors such as genetics, epigenetics, environment, lifestyle, and immune response. Aging is often defined as an age-related deterioration of physiological and cognitive functions necessary for survival and reproduction.

During aging, the brain undergoes various morphological, cellular, molecular, and functional changes leading to the occurrence of age-related cognitive decline. Healthy elderly people show significant decreases in brain volume and experience mild cognitive impairment (i.e. working memory & executive function) compared with younger adults. In patients with Alzheimer’s disease or other types of age-related dementia, the cognitive impairment is significantly more severe affecting daily life activities and requiring medical/professional assistance.

The idea of aging is something that is commonly feared by many, but what if it didn’t hurt to grow old? Imagine living independently longer. Less severe dementia. Later onset of cancer. Healthier heart and kidneys for longer. Klotho, a natural human protein has great potential to delay these diseases of aging. Loss of cognition, kidney failure, diabetes, and cancer are all things that are believed to be associated with the body’s production of this Klotho protein. Klotho Therapeutics (KTI) is using biotechnology to mimic the human protein.

Advantages

Advantages of Klotho Protein

Klotho is produced naturally in the kidneys of humans and animals and has been shown to have a positive impact not only on kidney function but also diseases associated with aging.

AGING

Aging, Cognition,
& Sarcopenia

Klotho is an anti-aging hormone detected in the brain, kidneys, urine, blood stream, and muscle. It is essential for a long, healthy life. Low Klotho levels have been associated with age-related disorders such as cardiovascular disease, diabetes, sarcopenia, and cognitive decline in both humans and laboratory animals.

CANCER

Cancer

Klotho shows great promise in the treatment of many types of cancer in animal studies. Klotho suppresses tumor growth, inhibits metastases, reduces resistance to chemo-therapy drugs and improves survival. Cancer is the leading cause of death in the US and new cancer cases are expected to grow 70% over the next 20 years; as most cancers are not curable.

KIDNEY DISEASE

Kidney Disease

The existing human and animal literature suggest that Klotho may be a promising biomarker for kidney disease and its symptoms. Future clinical studies should evaluate the safety and efficacy of Klotho therapy in CKD and AKI patients.

NEWS

Latest news on Klotho

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ASN Presentation

KTI Overview

Klotho Featured
in Longevity
Documentary